Can You Get Rejuran Treatments While on Accutane? Here's What You Really Need to Know

If you’re currently on Accutane (isotretinoin) and also dealing with acne scars, dry skin, or inflammation, you might be looking into Rejuran as a treatment option. You’ve likely heard about its ability to boost healing, improve skin texture, and support collagen production—all things your skin could really use during or after an acne journey.

But before you jump into scheduling an appointment, it’s important to ask:
Can you safely get Rejuran while on Accutane?
And even more importantly—should you?

At Qazi Cosmetic Center in Orange County, we specialize in acne scar revision and post-acne skin restoration for patients of all skin tones and treatment histories. We work with patients on Accutane every single week—whether they’re in the middle of their course or just finished it—and safety is always our first priority.

In this guide, we’re going to walk you through the risks, benefits, and expert recommendations on Rejuran while on Accutane so you can make an informed decision for your skin and your long-term results.

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What Is Rejuran?

Let’s start with the basics. Rejuran is a regenerative injectable treatment made from polynucleotides (PN)—DNA fragments derived from salmon that have powerful healing and anti-inflammatory properties. It’s sometimes called Rejuran Healer because it supports cell repair, improves skin texture, and strengthens the skin barrier.

Rejuran works best for:

• Post-acne inflammation
• Enlarged pores
• Skin that feels thin, rough, or uneven
• Skin that has been damaged or dried out from past treatments
• Subtle scarring or loss of elasticity

It’s especially popular in Korea and Singapore as a go-to treatment for sensitive or damaged skin, and we’re seeing more and more patients in the U.S. turn to Rejuran after finishing Accutane.

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What Accutane Does to Your Skin

Accutane (isotretinoin) is a systemic medication that changes how your skin behaves. It reduces oil production, shrinks sebaceous glands, and clears out deep, inflammatory acne—but it also comes with side effects.

While on Accutane, your skin may:

• Become dry or flaky
• Feel tight or sensitive
• Heal more slowly
• React more strongly to trauma or irritation

This is why many in-office treatments—like lasers, microneedling, or deep peels—are typically postponed until after Accutane is completed. The skin simply isn’t stable enough to handle injury while on isotretinoin.

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So, Can You Get Rejuran While on Accutane?

Technically? It depends. Practically? It’s usually better to wait.

Rejuran isn’t a laser or a peel—it’s a gentle injectable that doesn’t resurface or damage the skin. But even though it’s not aggressive, it’s still a medical procedure that involves microinjections. And anytime you break the skin’s surface while on Accutane, there’s a slightly increased risk of irritation, inflammation, or delayed healing.

At Qazi Cosmetic Center, we generally recommend waiting until at least 4–6 weeks after finishing Accutane before starting Rejuran. This gives your skin time to normalize and ensures that you get the full benefit of the treatment without unnecessary risks.

However, every patient is different—and in some lower-dose or short-duration cases, we may be able to adjust the timeline based on your skin's condition and response.

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What to Expect If You Start Rejuran After Accutane

Once your skin has stabilized post-Accutane, Rejuran can be an excellent way to rebuild skin quality and barrier health. Many of our patients start Rejuran treatments to address the long-term effects of Accutane, like dryness, inflammation, or textural issues.

Here's what Rejuran can do after Accutane:

• Rebuild moisture barrier damaged by months of dryness
• Reduce residual redness or irritation
• Soften mild scarring or texture changes
• Boost healing and collagen remodeling
• Improve pore size and elasticity

Rejuran is especially effective when paired with a customized routine of hydrating serums, barrier creams, and SPF—all of which we tailor to your skin at Qazi Cosmetic Center.

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How to Know When You’re Ready for Rejuran

We’ll help you determine the best time to start during your consultation, but here are some general signs that your skin may be ready:

• You’ve been off Accutane for at least 1 month (more if your dose was high)
• Your skin no longer feels tight, flaky, or irritated
• You're able to tolerate sunscreen and moisturizers without stinging
• You’re not dealing with any open breakouts or wounds
• You’ve talked to your dermatologist and cleared treatment plans

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Traveling from Out of State? We Make It Simple

Many of our acne scar and post-Accutane patients fly in for treatment. Whether you're coming from across the country or just outside Orange County, we’ve designed the process to be easy, efficient, and stress-free.

Here’s how we support out-of-town patients:

• Virtual consultations available 
• No need to call—book your appointment online
• Our clinic is just five minutes from John Wayne Airport
• Most patients fly in and return home the same day
• Airport staff are familiar with assisting Qazi patients and help streamline the visit

If you’d like help planning your trip, our team is happy to assist. Just call us at (949)-336-7293 and we’ll take care of the rest.

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Payment and Financing Options

We understand that healing your skin after Accutane is a journey—and we want to make that journey financially manageable.

We offer flexible payment options through:

• Cherry
• CareCredit
• Alpheon
• Affirm

Visit our financing page to see your options and apply.

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Key Takeaways: Rejuran While on Accutane

• Rejuran is a gentle injectable treatment that supports skin healing, hydration, and collagen production
• While it’s not aggressive, we typically recommend waiting 4–6 weeks after finishing Accutane to begin Rejuran
• Every case is unique—your timeline depends on your dose, skin condition, and goals
• Rejuran can help restore your skin after months of dryness, inflammation, and damage from isotretinoin
• We offer virtual consults and same-day travel options to make care accessible
• Financing plans are available to fit your budget

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Final Thoughts

Rejuran is one of the best treatments for restoring balance and health to post-Accutane skin. But timing matters.

At Qazi Cosmetic Center, we’ll help you create a personalized plan—one that honors your skin’s current state, supports long-term healing, and delivers natural, visible results. Whether you’ve just finished Accutane or you’re still on it, we’ll guide you every step of the way.

Book your virtual or in-person consultation today by clicking here or call (949)-336-7293.
Let’s get your skin back to balance—safely, strategically, and on your timeline.

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